ea0015p209 | Neuroendocrinology and behaviour | SFEBES2008
Bhogal Randip S
, Roux Carel W Le
, Ahweyevu Rukevwe A
, Bloom Steve R
, Ghatei Mohammad A
Background: Orlistat is a lipase inhibitor used in the treatment of obesity. Recent published work has shown that orlistat may have a role in affecting the release of appetite regulating gastrointestinal derived peptides. However, the precise effect of orlistat on these hormones remains uncertain. This study aimed to evaluate the short-term effects of orlistat with a high fat meal on levels of plasma Peptide YY (PYY) and on appetite.Methods: Ethical perm...